Chitosan Nanoparticles as a Sustained Delivery of Penicillin G prepared by ionic gelation technique

In the present scientific era, use of nanoparticles for antibiotic delivery is increasing due to increased prevalence of antibiotic resistant bacterial strains. The aim of this study was to formulate and characterize chitosan nanoparticles of penicillin G delivery to improve the bioavailability and prevent drug resistance. Method: In this work we took penicillin as drug of choice to demonstrate the efficacy of

chitosan nanoparticles against bacterial resistance. Ionic gelation technique was used to encapsulate penicillin G in chitosan nanoparticles

Website: http://www.arjonline.org/medicine-and-health-care/american-research-journal-of-pharmacy/