Evaluation of antioxidant potential and antimicrobial activity of successive extracts of Pimpinella tirupatiensis

1.       Pimpenella tirupatiensis (Apiaceae) is distributed in the forest of Tirupati in Andhra Pradesh commonly known as adavi kothimeera (Forest Coriander). It is used for the treatment of External inflammation, Diuretic, treatment of bladder distress, Asthma, Aphrodisiac, Skin diseases, Ulcers, Blood disorders, Toothache and Hepatoprotective. 1 Free radicals have been implicated to the causation of ailments such as liver cirrhosis, atherosclerosis, cancer, diabetes etc. 2 Reactive oxygen species such as super oxide anions (O2), hydroxyl radicals (OH) and nitric oxide (NO) inactivate the enzymes and damage important cellular components causing injury. 3 Antioxidants may offer resistance against the oxidative stress by scavenging the free radicals. Although living system possesses several natural defence mechanisms, such as enzymes and antioxidants nutrients, which arrest the chain reaction of ROS initiation and production. Many plants often contains substantial amounts of antioxidants including vitamins C and E, carotenoids, flavonoids, phenols and tannins etc. and thus can be utilized to scavenge the excess free radicals from the body.

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