It
may lead to gangrene and amputation of the lower extremities. Peripheral
neuropathy, peripheral arterial diseases in addition to immunosuppressant
contribute to the development of diabetic foot infection. Diabetic foot ulcers
are classified according to the size of the ulcer in addition to its depth,
site and appearance. Gram-positive cocci especially Staphylococcus aureus is
the predominant bacterial pathogen that infect diabetic foot ulcer.
However,
Gram-negative bacteria and anaerobes are involved in chronic infections. The
emergence of multidrug resistant bacteria and the formation of biofilms in
diabetic foot ulcers complicate their treatment. Treatment of diabetic foot
ulcer depends on medical and surgical intervention. Surgical removal of
necrotic and unhealthy tissues, pressure offloading, revascularization and
selection of proper wound dressing are important tools in the treatment of
diabetic foot ulcers. For choice of the proper antibiotic therapy, some factors
must be taken into consideration such as the wound culture results, the
severity of infection and the predominant bacteria.
No comments:
Post a Comment